Quantum Journal of Medical and Health Sciences

BIOMEDICAL ENGINEERING (BME) AND MEDICAL HEALTH SCIENCE: AN INVESTIGATION PERSPECTIVE EXPLORATION

2024-07-26T07:12:39+00:00

In the ever-evolving landscape, rapid advancements within the domains surrounding technological computing have brought about significant growth and transformation in the various types of biomedical engineering (BME) domains of engineering, medical engineering, health informatics particularly in the field of medical science and human health. With the accelerated progress in computer vision, image processing, machine learning, deep learning, and especially data science, there has been a booming revolutionary change in healthcare, addressing towards a wide range of the medical conditions and human anatomy perspectives. The integration of these technologies has not only improved medication and disease control but has also provided solutions for complex tasks and issues related to human anatomy threats in the medical health sector. This research focuses on the impact of these various types of innovative accelerated computing in biomedical engineering, providing insights into the modern utility of toolsets in line with Bioinformatics, Biomedical Applications and mechanics with artificial intelligence (AI) within medical science and also diving into a much deeper understanding towards the human anatomy. It also explores the concept of functional genomics and its potential to provide insights into future disease and health issues, paving the way for advancements in medical healthcare for the foreseeable future and beyond.

THE EFFECT OF FRAILTY ON BALANCE AND FALL RISK IN TYPE 2 DIABETIC PATIENTS

2024-05-22T10:05:31+00:00

The aim of this study was to examine the effect of frailty on balance and fall risk in individuals with type 2 diabetes mellitus (DM). A total of 50 individuals diagnosed with type 2 DM, including 25 frail and 25 non-frail individuals were included in the study. The demographic information of the individuals was collected using a prepared case data form. The frailty status of the individuals was evaluated using the Fried Frailty Index. Their cognitive status was assessed using the Standardized MiniMental Test (SMMT), fall risk was evaluated using the Self-Rated Fall Risk Questionnaire (FRQ) and the Falls Efficacy Scale-International. Balance assessment was conducted using the Tinetti Balance and Gait Assessment, Functional Reach Test and Timed Up and Go Test (TUG). The results of our study showed that the mean age of the frail group with type 2 diabetes was 69.08±4.17 years, while it was 67.96±3.41 years for the non-frail group. The average BMI of the individuals was found to be 29.42±3.81, and there was no significant difference in BMI values between the frail and non-frail groups. Statistical analysis revealed significant differences between the groups in Falls Efficacy Scale-International, FRQ, Tinetti Balance and Gait Assessment, Functional Reach Test, and TUG results (p<0.05). It was determined that individuals with type 2 diabetes who are frail have worse balance and a higher risk of falls compared to non-frail individuals. Fraility in individuals with Type 2 Diabetes can significantly affect balance and fall risk.

A PROSPECTIVE OBSERVATIONAL EXPLORATION OF MATERNAL AWARENESS OF NEONATAL JAUNDICE AND RISK ASSESSMENT

2024-05-26T16:51:29+00:00

Jaundice is the condition which is characterised by yellowish or greenish pigmentation of the skin and whites of the eyes due to high bilirubin levels. This condition is most commonly found in new-born and infants; however, it affects adults as well. Neonatal hyper bilirubinemia is the most common clinical condition in the newborn evaluation during the first week of postnatal life. Approximately 60% of term and 80% of preterm babies develop jaundice in the first week of life, and about 10% of breastfed babies are still jaundiced at 1 month of age. Jaundice is caused due to the accumulation of bilirubin (a yellow pigment) in the skin. When blood cells complete their life cycle, they are broken down in the body. Phototherapy and exchange transfusion are the mainstay of treatment for patients with unconjugated hyper bilirubinemia. Newborns with severe hyper bilirubinemia are at risk for bilirubin-induced neurologic dysfunction (BIND). The best prevention of infant jaundice is adequate feeding. Breast-fed infants should have eight to 12 feedings a day for the first several days of life. The primary goals of the current study are to evaluate the risk factors and maternal knowledge of neonatal jaundice and objective includes to educate mothers regarding neonatal jaundice and to increase the awareness about the neonatal jaundice. This survey highlights the mother's level of awareness of newborn jaundice. While mothers were aware of neonatal jaundice, their understanding of potential complications and treatment options was limited. Promoting awareness of neonatal jaundice among mothers is crucial for early detection and treatment, and during our study, the present study endeavoured to enhance mothers understanding of this condition.

USING STUDY STRATEGIES AND ITS CORRELATION WITH EDUCATIONAL STATUS IN STUDENTS OF PARAMEDICAL SCHOOL

2024-05-28T07:55:08+00:00

Students' academic success reaches its peak when they use study strategies correctly. The objective of study was to survey the use of study strategies and its correlation with educational status in paramedical students. This research was a descriptive-analytical study. The 220 students of laboratory sciences, operating room technology, radiology technology and anesthesiology were studied at Paramedical School. The research tool was a researcher-made questionnaire consisting of two parts included demographic information and the second part was related to the study strategies, which included 20 questions that were planned in the 5-point Likert scale. The data obtained from the questionnaire were analyzed by SPSS-22 software. In the result, the findings of the study showed that the comparison of the mean status of study strategies in terms of economic status was statistically significant (p=0.021) so that students with poor economic status had lower reading skills. In conclusion, it seems that it is necessary to introduce students with study skills upon entering the university through workshops or training courses in order to witness students' academic progress at higher level.

IN-VITRO COMPARATIVE QUALITY EVALUATION OF DIFFERENT BRANDS OF RANOLAZINE TABLETS MARKETED IN ANDHRA PRADESH, INDIA

2024-07-29T07:19:38+00:00

An extended-release tablet provides prolonged periods of drug in plasma levels thereby reduce dosing frequency, improve patient compliance and reduce the dose-related side effects. Ranolazine is indicated for the chronic treatment of angina in patients who have not achieved an adequate response with other anti-anginal agents. In this study, an attempt was made to investigate the in-vitro quality control testing of five different prominent pharmaceutical brands of Ranolazine hydrochloride tablets marketed in Andhra Pradesh, India. Five different brands of tablets used in the study, named brand A, brand B, brand C, brand D, and brand E were evaluated for weight variation, content uniformity, thickness, hardness, disintegration, dissolution, and assay. The study utilized standardized testing methods to ensure consistency and reliability across all assessments. Results revealed that all the brands of Ranolazine tablets complied with the official specification for hardness, friability, disintegration and assay. All the selected brands of Ranolazine tablets complied with the USP dissolution tolerance limits, the tablets demonstrated robust mechanical strength, minimal friability, and prompt disintegration of active pharmaceutical ingredients.

A COMPREHENSIVE EXPLORATION OF ADVANCES IN CERVICAL CANCER TREATMENT: TARGETED THERAPY, RADIOTHERAPY AND CHEMOTHERAPY

2024-06-06T09:43:47+00:00

Cancer is a complex group of diseases characterized by the uncontrolled growth and spread of abnormal cells. These cells can invade and destroy normal tissues and can also spread to other parts of the body through the bloodstream and lymphatic system. The development of cancer involves genetic mutations that disrupt the normal regulation of cell growth, leading to the formation of tumors. These tumors are of two types which describe the behaviour of tumor. They are benign and malignant. Malignant tumors can metastasize, or spread into, neighboring tissues, and can also generate new tumors by traveling to far-off regions of the body. Malignant tumors is another term for cancerous tumors, benign tumors do not penetrate or spread to neighboring tissues. Benign tumors typically don’t recur after removal. There exist more than 100 distinct types of cancer, each designated by the specific cell type or organ of origin. Each variation is characterized by unique causal factors, and cancer, being a preventable and treatable ailment, exhibits improved outcomes through early detection via screening. This research paper provides a comprehensive overview of cervical cancer, encompassing its epidemiology, risk factors, and cutting-edge advancements in preventive and therapeutic strategies. Beyond conventional approaches, such as surgery and chemotherapy, the paper examines the efficacy and potential of targeted therapy, radiation therapy, and immunotherapy in combating cervical cancer. These therapeutic strategies offer hopeful paths for individualized treatment, leading to enhanced outcomes for patients.